منابع مشابه
Mutagenicity test of cefodizime sodium.
The mutagenicity of cefodizime sodium (THR-221) was investigated by the reverse mutation test using seven bacterial strains (Salmonella typhimurium strains TA100, TA98, TA1535, TA1537 and TA1538, and Escherichia coli strains WP2 and WP2uvrA) and the chromosomal aberration test with cultured Chinese hamster lung (CHL) cells. The reverse mutation test was carried out in dose range from 0.0025 to ...
متن کاملMutagenicity of glutathione and cysteine in the Ames test.
Postmitochondrial supernatant from rat liver and kidney homogenates transformed cysteine into a mutagen that reverted bacteria of the strain Salmonella typhimurium TA100 to histidine independence. Glutathione was also activated by kidney postmitochondrial supernatant but not by liver preparations. Hence, important endogenous compounds of mammals are positive in the most commonly used short-term...
متن کاملEvolutionary Ensemble for In Silico Prediction of Ames Test Mutagenicity
Driven by new regulations and animal welfare, the need to develop in silico models has increased recently as alternative approaches to safety assessment of chemicals without animal testing. This paper describes a novel machine learning ensemble approach to building an in silico model for the prediction of the Ames test mutagenicity, one of a battery of the most commonly used experimental in vit...
متن کاملMutagenicity of flavonoids assayed by bacterial reverse mutation (Ames) test.
The mutagenicity of ten flavonoids was assayed by the Ames test, in Salmonella typhimurium strains TA98, TA100 and TA102, with the aim of establishing hydroxylation pattern-mutagenicity relationship profiles. The compounds assessed were: quercetin, kaempferol, luteolin, fisetin, chrysin, galangin, flavone, 3-hydroxyflavone, 5-hydroxyflavone and 7-hydroxyflavone. In the Ames assay, quer...
متن کاملstudents perception of computerized toefl test
تحقیق حاضر به بررسی درک دانشجویان از مزایا و معایب آزمون های کامپیوتری تافل و تاثیر جنسیت بر درک آنها پرداخته است. شرکت کنندگان در این تحقیق 100 نفرزبان آموز مرد و زن بودند که در آزمون کامپیوتری تافل در ایران شرکت کرده بودند. پرسشنامه یی که در مورد مزایا و معایب آزمون های کامپیوتری در مقایسه با آزمون های کاغذی توسط محقق تهیه شده بود جهت تکمیل به این افراد ارایه شد. داده های بدست آمده در این مطا...
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ژورنال
عنوان ژورنال: The Journal of Toxicological Sciences
سال: 1988
ISSN: 0388-1350,1880-3989
DOI: 10.2131/jts.13.supplementi_245